Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Structures of 5-Bromodeoxyuridine and 5-Bromouridine

Abstract

HALOGENATED deoxyuridines can be incorporated into DNA in place of the normal thymidine component, and this affects the physical properties of the DNA and has important biological consequences. For example, it makes DNA more sensitive to ultra-violet radiation1 and it produces mutagenic changes2.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Erikson, R. L., and Szybalski, W., Biochem. and Biophys. Res. Commun., 4, 258 (1961).

    Article  CAS  Google Scholar 

  2. Freese, E., Proc. U.S. Nat. Acad. Sci., 45, 622 (1959).

    Article  ADS  CAS  Google Scholar 

  3. Camerman, N., and Trotter, J., Acta Cryst., 18, 203 (1965).

    Article  CAS  Google Scholar 

  4. Donohue, J., and Trueblood, K. N., J. Mol. Biol., 2, 363 (1960).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

IBALL, J., MORGAN, C. & WILSON, H. Structures of 5-Bromodeoxyuridine and 5-Bromouridine. Nature 209, 1230–1232 (1966). https://doi.org/10.1038/2091230b0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/2091230b0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing