Abstract
CELLULAR differentiation has proved to be one of the most fascinating subjects for investigations in the field of biology. Since Spemann's1 discovery of the phenomenon of induction by organizers, numerous investigations have been directed towards the isolation and identification of inductor substances in morphogenesis. Efforts to obtain such genotropic substances and to analyse the mechanisms of their actions have so far been unsuccessful. In my investigations, bacterial sporogenesis has been taken as a model system for studying the biochemical aspects of intracellular differentiation.
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References
Spemann, H., and Mangold, H., Roux Arch. Entwicklugsmechanik, 100, 599 (1924).
Srinivasan, V. R., and Orin Halvorson, H., Nature, 197, 100 (1963).
Monod, J., Jacob, F., and Gros, F., Biochem. Soc. Symp., 21, 104 (1962).
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SRINIVASAN, V. Sporogen—an ‘Inductor’ for Bacterial Cell Differentiation. Nature 209, 537 (1966). https://doi.org/10.1038/209537a0
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DOI: https://doi.org/10.1038/209537a0
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