Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Prolonged Survival of Isolated Frog Muscle and its Sensitivity to Acetylcholine

Nature volume 209, pages 716–717 (1966)Cite this article

Abstract

IN adult muscle fibres the membrane sensitivity to acetylcholine is restricted to the neuromuscular junction and its immediate surrounding1; but if the muscle is deprived of its motor innervation the entire muscle fibre surface becomes sensitive to acetylcholine2,3.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Miledi, R., J. Physiol., 151, 24 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Axelsson, J., and Thesleff, S., J. Physiol., 147, 178 (1959).

    Article  CAS  Google Scholar 

  3. Miledi, R., J. Physiol., 151, 1 (1960).

    Article  CAS  Google Scholar 

  4. Miledi, R., and Trowell, O. A., Nature, 194, 981 (1962).

    Article  ADS  CAS  Google Scholar 

  5. Katz, B., and Miledi, R., J. Physiol., 170, 379 (1964).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biophysics, University College, London

    A. J. HARRIS & R. MILEDI

Authors
  1. A. J. HARRIS
    View author publications

    Search author on:PubMed Google Scholar

  2. R. MILEDI
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

HARRIS, A., MILEDI, R. Prolonged Survival of Isolated Frog Muscle and its Sensitivity to Acetylcholine. Nature 209, 716–717 (1966). https://doi.org/10.1038/209716a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/209716a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing