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Isolation of 2-Aminoethylphosphonic Acid from Phospholipids of the Abalone (Haliotis midae)

Abstract

IN the course of an investigation of the phospholipids of the abalone shellfish (Haliotis midae), a ninhydrin-reactive substance was detected which showed properties similar to phosphoryl ethanolamine. For example, no separation between phosphoryl ethanolamine and the unknown compound was obtained by column chromatography on the cation exchange resin ‘Amberlite C.G. 120’ type 2 with an eluting buffer of pH 3.25. Hydrolysis with 2 N hydrochloric acid at 120° C for 100 h failed, however, to liberate ethanolamine and phosphoric acid. This substance was identified as 2-aminoethylphosphonic acid.

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DE KONING, A. Isolation of 2-Aminoethylphosphonic Acid from Phospholipids of the Abalone (Haliotis midae). Nature 210, 113 (1966). https://doi.org/10.1038/210113a0

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