Abstract
IN the course of a continuous survey1,2 on the occurrence and levels of activity of ornithine–urea cycle3 enzymes, an unexpected opportunity was afforded for quantitative measurement of these activities in the instance of the African lion, Felis leo. At the Vilas Park Zoo in Madison (Wisconsin) the director, Mr. Dan Watson, decided that an infirm male lion about twelve years old had to be destroyed. The lion exhibited progressive difficulty in its ability to leap to a platform some 2 m high in the cage; this created a feeding problem and difficulty in moving the animal to an outside exercise yard.
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Brown, jun., G. W., and Cohen, P. P., Biochem. J., 75, 82 (1960).
Cohen, P. P., and Brown, jun., G. W., in Comparative Biochemistry, edit. by Florkin, M., and Mason, H. S., 2, 161 (Academic Press, New York, 1960).
Krebs, H. A., and Henseleit, K., Z. Physiol. Chem., 210, 33 (1932).
Brown, jun. G. W., and Cohen, P. P., J. Biol. Chem., 234, 1769 (1959).
Ratner, S., in Methods in Enzymology, edit. by Colowick, S. P., and Kaplan, N. O., 2, 356 (Academic Press, New York, 1955).
Clementi, A., Arch. Fisiol., 13, 189 (1915).
Fuchs, B., Z. Physiol. Chem., 114, 101 (1921).
Iseki, T., and Imamura, H., Z. Physiol. Chem., 270, 28 (1941).
Greenstein, J. P., Jenrette, W. V., Mider, G. B., and White, J., J. Nat. Cancer Inst., 1, 687 (1940–41).
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BROWN, G. Urea Cycle Enzyme Activities of Liver of the African Lion. Nature 210, 1367 (1966). https://doi.org/10.1038/2101367a0
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DOI: https://doi.org/10.1038/2101367a0


