Abstract
IN this laboratory we have been interested in the existence of a possible soluble precursor of insoluble elastin (tropoelastin) analogous to tropocollagen. However, since elastin has no enzyme activity and does not possess a specific amino-acid, such as occurs in collagen, no simple method was available to detect this protein in the presence of large amounts of other proteins, which are found in tissue extracts.
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Ayer, J., and Feldmanis, L., Fed. Proc., 17, 1 (1958).
Walford, R. L., Hirose, F. M., and Doyle, P., Lab. Invest., 8, 948 (1959).
Marceau, G., Laval Med., 34, 882 (1963).
Robert, L., Parlebas, J., Poullain, N., and Roberts, B., Protides of the Biological Fluids, 2, 109 (1963).
Partridge, S. M., Davis, H. F., and Adair, G. S., Biochem. J., 61, 11 (1955).
Cleary, E. G., Jackson, D. S., and Sandberg, L. B. (in the press).
Ouchterlony, O., Acta Pathol. Microbiol. Scand., 26, 507 (1949).
Scheidegger, J. J., Intern. Arch. Allergy, App. Immunol., 7, 103 (1955).
Ovary, Z., Prog. Allergy, 5, 459 (1958).
Butler, W. T., J. Immunol., 90, 663 (1963).
Stavitsky, A. B., J. Immunol., 72, 360 (1954).
Jackson, D. S., Sandberg, L. B., and Cleary, E. G., Biochem. J., 96, 813 (1965).
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JACKSON, D., SANDBERG, L. & CLEARY, E. Antigenic Properties of Soluble Elastins and their Use in Detecting Soluble Elastin in Ligament Extracts. Nature 210, 195–196 (1966). https://doi.org/10.1038/210195a0
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DOI: https://doi.org/10.1038/210195a0