Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Measurement of the Absolute Disintegration Rate of Technetium-99m

Abstract

TECHNETIUM-99m is becoming an important tracer for many diagnostic investigations; for example, brain scanning and thyroid scanning1,2. Its chief advantages are that it has a short half-life and emits an essentially mono-energetic γ-ray which is only slightly internally converted. Hence quite large activities of technetium-99m can be safely administered to patients. So far this nuclide has only been assayed by comparing it with a standard of some other nuclide—for example, cobalt-57 (ref. 3)—and no absolute measurements have been reported. However, as will be shown here, it is possible to make an absolute measurement by the 4πβ-γ coincidence technique4. (The National Physical Laboratory plans to distribute standards of technetium-99m, calibrated by this technique, in October 1966, to users within 12 h travelling time of Teddington.)

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. McAfee, J. G., Fueger, C. F., Stern, H. S., Wagner, H. N., and Migita, T., J. Nucl. Med., 5, 811 (1964).

    CAS  PubMed  Google Scholar 

  2. Tothill, P., and Irvine, W. J., Radioaktiv Isotopen in Klinik und Forschung, 6 (in the press).

  3. Smith, E. M., J. Nucl. Med., 5, 871 (1964).

    CAS  PubMed  Google Scholar 

  4. Campion, P. J., Intern. J. App. Rad. Isotop., 4, 232 (1959).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GOODIER, I., WILLIAMS, A. Measurement of the Absolute Disintegration Rate of Technetium-99m. Nature 210, 614–615 (1966). https://doi.org/10.1038/210614b0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/210614b0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing