Abstract
SINCE their discovery1–4, the effects of midbrain stimulation on excitability of the visual system have been studied extensively. Work on the squirrel monkey5,6 has shown that the centrencephalic system exerts a powerful control over transmission through the lateral geniculate nucleus (LGN) for both photically and electrically elicited responses. Initial experiments showed facilitation following electrical stimulation of the mesencephalic reticular formation or natural alerting stimuli. Recent experiments, however, have shown that a brief period of inhibition precedes the facilitation and, as set forth below, strongly suggest that this inhibition is presynaptic in nature.
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PECCI-SAAVEDRA, J., WILSON, P. & DOTY, R. Presynaptic Inhibition in Primate Lateral Geniculate Nucleus. Nature 210, 740–742 (1966). https://doi.org/10.1038/210740a0
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DOI: https://doi.org/10.1038/210740a0
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