Abstract
THE chromosome breaking ability of l-threitol 1,4-bis-methanesulphonate was investigated in three plant species1. Chemical and cytological2,3 evidence supports the fact that this compound can transform slowly in vivo into an active bisepoxide. The differential mutagenic activity of the l(+) and d(−) isomers of bispoxybutane was investigated in Penicillium multicolor and in Vicia faba4. The l isomer exerted a higher activity.
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References
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Moutschen, J., La Cellule, 65, 161 (1965).
Moutschen-Dahmen, J., and M., and Loppes, R., Nature, 199, 406 (1963).
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MOUTSCHEN, J., MATAGNE, R. & GILOT, J. Chromosome Breakage with Two Isomers of l-Threitol 1,4-bismethanesulphonate in Plants. Nature 210, 762–763 (1966). https://doi.org/10.1038/210762a0
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DOI: https://doi.org/10.1038/210762a0
