Growth of L1210 Leukaemia Cells

Abstract

THERE is evidence that the number or size of the cell inoculum, the site of inoculation, the host of origin or the conditioning of the host¹ can alter the strain specificity of neoplasms and that some neoplasms can be transplanted from strain of origin and grow progressively in homologous strains with the animals dying of the neoplastic disease. Greene² reported the successful transplantation of heterologous neoplasms into the brains of rats and mice and suggested that the brain might be exempt from any immunological response.