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Presence of Adenosine Triphosphate in the Skin Venom of Amphibia

Abstract

PRUSOFF'S discovery of adenosine triphosphate (ATP) and 5-hydroxytryptamine (5-HT) in enterochromaffin cell granula1 stimulated us to an attempt to extend this observation to other sections of Erspamer's enterochromaffin cell system2,3. In a preliminary investigation4,5 we demonstrated the existence of ATP in “venom” squeezed manually from the parotoid glands of Bufo vulgaris and viridis, while we were unable to observe ATP in venom from Salamandra maculosa and Salamandra atra with the procedure used at that time.

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VIALLI, M., BOLOGNANI, L. Presence of Adenosine Triphosphate in the Skin Venom of Amphibia. Nature 211, 1324 (1966). https://doi.org/10.1038/2111324a0

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