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Two-dimensional Thin-layer Chromatography of the Major Mononucleotides of Ribonucleic Acid

Nature volume 211, pages 414–415 (1966)Cite this article

Abstract

THIN-LAYER chromatography, by virtue of its convenience, sensitivity, and short developing time, is useful for the separation and quantitation of many types of nucleic acid derivatives1–3. This communication describes the method used by this laboratory for the separation of the products of alkaline hydrolysis of ribonucleic acid.

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References

  1. Josefsson, L., Biochim. Biophys. Acta, 72, 133 (1963).

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  2. Grippo, P., Iaccarino, M., Rossi, M., and Scarano, E., Biochim. Biophys. Acta, 95, 1 (1965).

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  3. Randerath, K., Nature, 205, 908 (1965).

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Authors and Affiliations

  1. Department of Medicine, Northwestern University Medical School, Chicago, Illinois

    JASON L. STARR & BONNIE RAMBERG

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  1. JASON L. STARR
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  2. BONNIE RAMBERG
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STARR, J., RAMBERG, B. Two-dimensional Thin-layer Chromatography of the Major Mononucleotides of Ribonucleic Acid. Nature 211, 414–415 (1966). https://doi.org/10.1038/211414b0

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