Abstract
LYSOSOMES are usually investigated in subcellular fractions and in preparations of fixed cells. The detection of these structures in living cells is an important task of modern cytology. This communication deals with the possibilities of detecting such structures that can be achieved by fluorescence microscopic methods.
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References
Vonkennel, and Wiedmann, Dtsch. Med. Wschr., 70, 529 (1944).
Schümmelfeder, N., Virchow's Archiv., 319, 294 (1950).
Meissel, M. N., Kondratieva, T. M., and Emeljanov, K. N., Dokl. Akad. Nauk S.S.S.R. (in Russian), 81, 1047 (1951).
Kosenow, W., Acta Haematol., 7, 217 (1952).
Bertalanffy, von L., and Bickis, J., J. Histochem. Cytochem., 4, 481 (1956).
Zelenin, A. V., and Khruschov, N. G., Problemi Hematologii i Perelivanija Krovi (in Russian), 3, 26 (1964).
Meissel, M. N., and Korchagin, V. B., Bull. Exp. Biol. Med. (in Russian), 33, 49 (1952).
Venetta, B. D., and Shure, A. Q., Exp. Cell Res., 24, 570 (1961).
Eichner, D., Z. Zellforsch., 49, 418 (1959).
Wolf, M. K., and Aronson, S. B., J. Histochem. Cytochem., 9, 22 (1961).
Zelenin, A. V., and Liapunova, E. A., in Second Intern. Cong. Histo- and Cytochem., 217 (1964).
Zelenin, A. V., Birjusova, V. I., Vorotnitskaja, N. E., and Liapunova, E. A., Dokl. Akad. Nauk S.S.S.R. (in Russian), 162, 925 (1965).
Robbins, E., Marcus, Ph. I., and Gonatas, N. K., J. Cell Biol., 21, 49 (1964).
Ogawa, K., Mizuno, N., and Okomoto, M., J. Histochem. Cytochem., 9, 635 (1961).
Koenig, H., J. Histochem. Cytochem., 11, 120 (1963).
Allison, A. C., and Mallucci, L., Nature, 203, 1024 (1964).
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ZELENIN, A. Fluorescence Microscopy of Lysosomes and Related Structures in Living Cells. Nature 212, 425–426 (1966). https://doi.org/10.1038/212425a0
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DOI: https://doi.org/10.1038/212425a0
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