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Function of Redox Systems in Melanophore Receptors

Abstract

THE melanophore movement of the frog skin is a convenient slow motion model for the pharmacological receptor1–3. It has been shown that oxidizing agents, which have very low redox potentials, induce dispersion of melanophore, an effect similar to that of xanthines or hormones that stimulate melanophore. On the other hand, reduction or succinate cause melanophores to contract2. It was also shown that melanophore dispersion is accompanied by loss of energy, while for melanophore contraction energy must be supplied2,3.

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References

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  2. Dikstein, S., Tal, E., and Sulman, F. G., Biochem. Pharmacol., 14, 1151 (1965).

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TAL, E., DIKSTEIN, S. & SULMAN, F. Function of Redox Systems in Melanophore Receptors. Nature 212, 851 (1966). https://doi.org/10.1038/212851a0

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