Abstract
IN 1952 Skeggs et al.1 published a method for extracting angiotensin from blood, and several authors have since dealt with the measurement of circulating angiotensin in man and experimental animals2–6. In all cases the concentration of angiotensin was measured by bioassay in the rat. The concentrations of circulating angiotensin found by these methods in normal and hypertensive subjects, and in experimental animals, are variable. This may be either because of variable recoveries or because of the inaccuracies inherent in bioassay.
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References
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OSBORN, E. Estimation of Angiotensin in Blood by the Preparation of Isotopic Derivatives. Nature 212, 950 (1966). https://doi.org/10.1038/212950a0
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DOI: https://doi.org/10.1038/212950a0
