Abstract
IT has been shown previously1–3 that immunological responses to protein antigens can be inhibited by administration in advance of large quantities of unrelated proteins. A similar inhibition can also be produced when two antigens are given simultaneously in the same emulsion of Freund's adjuvant4,5. Competition between antigens occurs when synthetic antigenic determinants of different specificity attached to the same non-antigenic protein molecule are injected into rabbits6.
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EFRAIM, S., LIACOPOULOS, P. Inhibition of Delayed Hypersensitivity in Guinea-pigs after Competition between Synthetic Antigens. Nature 213, 711–713 (1967). https://doi.org/10.1038/213711a0
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DOI: https://doi.org/10.1038/213711a0
