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Levels of Monoamine Oxidase in the Brain of C57BL/6J Mice after Exposure to Defeat

Nature volume 213, pages 739–740 (1967)Cite this article

Abstract

IT has been widely demonstrated during the past several years that changes in brain levels of serotonin have a direct effect on changes in behaviour1–12. Norepinephrine has also been shown to be directly involved with behaviour9,13. In addition, norepinephrine has been demonstrated to be connected with the behavioural changes observed when an animal is attacking or being attacked14, and both serotonin and norepinephrine have been reported to be involved in the learning ability of mice15–17. These observations were all made after changing the brain amine levels by the administration of drugs or by electrically stimulating the brain. No work, however, has been reported to show the effect of purely behavioural manipulation on the brain amine levels.

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Authors and Affiliations

  1. Department of Zoology, Kansas State University, Manhattan, Kansas

    K. W. BOEHLKE & B. E. ELEFTHERIOU

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  1. K. W. BOEHLKE
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  2. B. E. ELEFTHERIOU
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BOEHLKE, K., ELEFTHERIOU, B. Levels of Monoamine Oxidase in the Brain of C57BL/6J Mice after Exposure to Defeat. Nature 213, 739–740 (1967). https://doi.org/10.1038/213739a0

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