Abstract
PEARSON1 has recently presented evidence which suggests, that human urine may contain appreciable quantities of non-exchangeable calcium. Urine, labelled with calcium-47 in calcium chloride, was passed through a column of ‘Zeokarb 225’ cation exchange resin and the effective non-exchangeable calcium (CNE) was calculated, using the following expression: 
where A1 and A2 are the original and final count rates (c.p.m.) and C1 and C2 the initial and final concentrations, of chemical calcium (mg per cent).
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References
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Nordin, B. E. C., and Smith, D. A., Diagnostic Procedures in Disorders of Calcium Metabolism (Churchill, London, 1965).
Spare, P. D., Clin. Chem., 10, 726 (1964).
Raaflaub, J., Helv. Med. Acta, 30, 724 (1963).
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HODGKINSON, A., ZAREMBSKI, P. & NORDIN, B. Non-exchangeable Calcium in Human Urine. Nature 214, 1045–1046 (1967). https://doi.org/10.1038/2141045a0
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DOI: https://doi.org/10.1038/2141045a0
