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Low Frequency Sound and Oxytocic Activity of Plasma in Rats

Abstract

NATURAL thunder—a playback of recorded thunder—with a predominant frequency of 150 c/s at an intensity of 98–100 dB has caused diuresis and increased urinary outputs of sodium and potassium in rats1. These responses were similar to those caused by subcutaneous injections of 4.0 mU of oxytocin and the results of all investigations indicated that these urinary responses to low frequency sound were caused by the release of oxytocin1. The purpose of this communication is to report direct confirmation of these indications.

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OGLE, C. Low Frequency Sound and Oxytocic Activity of Plasma in Rats. Nature 214, 1112–1113 (1967). https://doi.org/10.1038/2141112a0

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