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Nuclear Sex of Testicular Teratomas of Infants

Abstract

ABOUT a third to a half of the testicular teratomas of adults are positive for female sex chromatin according to the Barr technique1–3. This observation is in accord with theories of origin of these tumours from haploid germ cells, either by auto-fertilization or by parthenogenesis. Testicular teratocarcinomas of the mouse arise during foetal life long before morphological evidence of meiosis, and so it is not surprising that they are karyotypic males in agreement with the sex of the host4.

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PIERCE, G., NAKANE, P. Nuclear Sex of Testicular Teratomas of Infants. Nature 214, 820–821 (1967). https://doi.org/10.1038/214820a0

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