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Effect of Chlordiazepoxide on Stomach Ulcers in Rabbit induced by Stress

Nature volume 215, page 1183 (1967)Cite this article

Abstract

IN an earlier communication1 we reported that premedication with chlordiazepoxide (CDP), a 1,4-benzodiazepine derivative, prevented the eosinopenia caused by emotional stress in rabbits, acting in a manner antagonistic to adrenocorticotrophic hormone (ACTH). Furthermore, CDP behaves antagonistically towards another hormone involved in stress, namely, antidiuretic hormone2. The effect of premedication with CDP on stomach ulcers induced by stress has now been investigated.

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References

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Authors and Affiliations

  1. Department of Pharmacology, Institute of Basic Medical Sciences, University College of Medicine, Calcutta University,

    S. R. DASGUPTA & B. P. MUKHERJEE

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  1. S. R. DASGUPTA
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  2. B. P. MUKHERJEE
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DASGUPTA, S., MUKHERJEE, B. Effect of Chlordiazepoxide on Stomach Ulcers in Rabbit induced by Stress. Nature 215, 1183 (1967). https://doi.org/10.1038/2151183a0

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