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Effect of α-Methyl Dopa on Acetylcholine Content of Rat Brain, Heart and Intestine

Abstract

RESERPINE, guanethidine and syrosingopine, which are potent hypotensive drugs, have been shown to produce side effects suggestive of increased parasympathetic activity. Some of these effects, such as bradycardia and diarrhoea, are attributable to an increased acetylcholine content of heart and intestine1, 2.

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BHARGAVA, V. Effect of α-Methyl Dopa on Acetylcholine Content of Rat Brain, Heart and Intestine. Nature 215, 202 (1967). https://doi.org/10.1038/215202a0

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