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Increased Lactate Dehydrogenase 3 in Serum after Myocardial Infarction

Nature volume 215, pages 287–289 (1967)Cite this article

Abstract

SINCE the first report of lactate dehydrogenase (LDH) isoenzymes in human serum1 a variety of different techniques has been employed to demonstrate them in serum and tissues. There is general agreement, however, that heart muscle contains predominantly the fast-moving isoenzymes lactate dehydrogenase 1 and 2 and that these are present in increased quantities in the sera of patients who have suffered a myocardial infarction, remaining demonstrably elevated for 1–3 weeks after the onset of the attack2.

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References

  1. Vesell, E. S., and Bearn, A. G., Proc. Soc. Exp. Biol. N.Y., 94, 96 (1957).

    Article  CAS  Google Scholar 

  2. Latner, A. L., and Skillen, A. W., Lancet, ii, 1286 (1961).

  3. Warburton, F. G., and Waddecar, J., J. Clin. Path., 19, 517 (1966).

    Article  CAS  Google Scholar 

  4. Barnett, H., J. Clin. Path., 17, 567 (1964).

    Article  CAS  Google Scholar 

  5. Kreutzer, H. H., and Eggels, P. H., Clin. Chim. Acta, 12, 80 (1965).

    Article  CAS  Google Scholar 

  6. Weime, R. J., Clin. Chim. Acta, 13, 138 (1966).

    Article  Google Scholar 

  7. Ressler, N., Joseph, R., and Schulz, J., J. Lab. Clin. Med., 60, 2, 349 (1962).

    Google Scholar 

  8. Wroblewski, F., and Gregory, K. F., Ann. N.Y. Acad. Sci., 94, 3, 912 (1961).

    Google Scholar 

  9. Latner, A. L., Proc. Assoc. Clin. Biochem., 11, 6 (1962).

    Google Scholar 

  10. Weime, R. J., Nature, 199, 437 (1963).

    Article  ADS  Google Scholar 

  11. Walter, G. B., and Israel, M. S., General Pathology (second ed.), 34, 656 (1965).

    Google Scholar 

  12. Wells, R. E., Anaesthetology, 24, 828 (1963).

    Article  Google Scholar 

  13. Wilkinson, J. H., Isoenzymes, 4, 44 (1965).

    Google Scholar 

  14. Plummer, D. T., Elliott, B. A., Cooke, K. B., and Wilkinson, J. H., Biochem. J., 87, 416 (1963).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pathology and Casualty Department, Hope Hospital, Salford, 6

    F. G. WARBURTON, E. ALLAN & G. S. LAING

  2. Department of Biochemistry, Park Hospital, Davyhulme, Nr. Manchester

    J. WADDECAR

Authors
  1. F. G. WARBURTON
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  2. E. ALLAN
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  3. G. S. LAING
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  4. J. WADDECAR
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WARBURTON, F., ALLAN, E., LAING, G. et al. Increased Lactate Dehydrogenase 3 in Serum after Myocardial Infarction. Nature 215, 287–289 (1967). https://doi.org/10.1038/215287a0

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