Abstract
THERE are some indications that diabetes mellitus is a disease involving a disorder of carbohydrate, lipid and protein metabolism. Leucocytes possess a nucleus and mitochondria, and metabolize glucose, amino-acids and fatty acids, and therefore might be useful for the investigation of certain aspects of metabolism in human diabetes. Investigation of glucose uptake and oxidation, lipid metabolism and lactic acid formation in leucocytes has had varied results1–3. Protein synthesis has not been investigated in leucocytes, and we aimed to determine the differences in protein metabolism in leucocytes from control and diabetic patients.
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References
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Munroe, J., and Shipp, J., Diabetes, 14, 584 (1964).
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TOKODI, I., POZSÁR, B. Protein Synthesis in Leucocytes of Diabetic and Normal Subjects. Nature 215, 300–301 (1967). https://doi.org/10.1038/215300a0
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DOI: https://doi.org/10.1038/215300a0
