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Ultrastructural Localization of Coxsackie B4 Virus in Mouse Myocardium

Abstract

COXSACKIE viral infections are known to cause myocardial lesions in various animal species1. The identification and localization of the Coxsackie viral particles in the heart have not been adequately demonstrated because of the absence of morphological criteria which will differentiate virus particles from glycogen granules and ribosomes. This communication describes the ultrastructural localization of Coxsackie B4 virus particles in the mouse heart by a ferritin antibody technique.

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SOHAL, R., SUN, S., BURCH, G. et al. Ultrastructural Localization of Coxsackie B4 Virus in Mouse Myocardium. Nature 215, 312–313 (1967). https://doi.org/10.1038/215312b0

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