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Protection of Canine Pancreatic Ultrastructure against Radiation Damage by Post-treatment with Alloxan

Abstract

IN a previous study1 we demonstrated that pretreatment of dogs with a single small, non-diabetogenic dose of alloxan monohydrate (15 mg/kg) intravenously protects the pancreatic ultrastructure against severe irradiation damage.

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References

  1. Volk, B. W., Wellmann, K. F., and Lazarus, S. S., Amer. J. Pathol., 51, 207 (1967).

    CAS  Google Scholar 

  2. Volk, B. W., Wellmann, K. F., and Lewitan, A., Amer. J. Pathol., 48, 721 (1966).

    CAS  Google Scholar 

  3. Wellmann, K. F., Volk, B. W., and Lewitan, A., Lab. Invest., 15, 1007 (1966).

    CAS  Google Scholar 

  4. Volk, B. W., and Wellmann, K. F., The Effect of Radiation on Ultrastructure and Enzymes of Canine Pancreas in Symp. on Gastrointestinal Radiation Injury (in the press).

  5. Doolittle, D. P., and Watson, J. A., Intern. J. Radiat. Biol., 11, 389 (1966).

    CAS  Google Scholar 

  6. Stöcker, E., Hauswaldt, C., and Klinge, O., Experientia, 21, 512 (1965).

    Article  Google Scholar 

  7. Stöcker, E., Hauswaldt, C., and Klinge, O., Beitr. Pathol. Anat., 133, 1 (1966).

    PubMed  Google Scholar 

  8. Lazarow, A., in Experimental Diabetes (edit. by Delafresnaye, J. F., and Smith, G. H.), 49–79 (Charles C. Thomas, Springfield, Ill., 1954).

    Google Scholar 

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WELLMANN, K., VOLK, B. & LAZARUS, S. Protection of Canine Pancreatic Ultrastructure against Radiation Damage by Post-treatment with Alloxan. Nature 216, 86–87 (1967). https://doi.org/10.1038/216086a0

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