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Rate of Release of Iron from Ferritin to 1,10-Phenanthroline

Abstract

ALTHOUGH the uptake and release of iron from ferritin, the principal form in which iron is stored by mammals, have been examined qualitatively1 and the rate of uptake has been studied previously2, there have been no previous studies of the rate of release of iron. We report here the results of a study of the rate of in vitro release of iron from ferritin in the presence of 1,10-phenanthroline. The effects of ascorbic acid, as well as concentration and temperature, were determined.

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References

  1. Sturgeon, P., and Shoden, A., Iron Metabolism, Intern. Symp. Aix-en-Provence, France, 121 (1963).

  2. Loewdes, M. W., and Fineburg, R. A., Biochim. Biophys. Acta, 26, 441 (1957).

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  3. Novak, J., Talanta, 12, 649 (1965).

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JONES, M., JOHNSTON, D. Rate of Release of Iron from Ferritin to 1,10-Phenanthroline. Nature 216, 509–510 (1967). https://doi.org/10.1038/216509a0

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