Abstract
FOLLICLE-STIMULATING hormone (FSH) is able to induce the formation of neural tissue and, in some instances, support differentiation of notochord-like and somitic tissues in chick embryonic systems. Recent experiments have suggested that the primary mesoderm is the target tissue for FSH1–6. The latter observation may be of some interest in view of the part played by the mesoderm in the establishment of the embryonic axis. The antigen–antibody reaction is a sensitive and specific reaction. We have attempted, using specific antisera, to obtain some information about the possible importance of FSH or FSH-like glycoproteins in embryonic development.
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References
Sherbet, G. V., Naturwissenschaften., 49, 471 (1962).
Sherbet, G. V., J. Embryol. Exp. Morphol., 10, 227 (1963).
Sherbet, G. V., and Lakshmi, M. S., Nature, 215, 1089 (1967).
Sherbet, G. V., and Lakshmi, M. S., Experientia, 23, 969 (1967).
Sherbet, G. V., and Mulherkar, L., Roux. Arch. Entwickl. Mech., 154, 506 (1963).
Sherbet, G. V., and Mulherkar, L., Roux. Arch. Entwickl. Mech., 155, 701 (1965).
New, D. A. T., J. Embryol. Exp. Morphol., 3, 326 (1955).
Butt, W. R., Crooke, A. C., and Cunningham, F. J., in Immunoassay of Hormones, Ciba Foundation Colloquia on Endocrinology (edit. by Wolstenholme, G. E. W., and Cameron, M. C.), 310 (J. and A. Churchill, London, 1962).
Denis, H., J. Mol. Biol., 22, 285 (1966).
Sherbet, G. V., in Histones, Their Role in the Transfer of Genetic Information, Ciba Foundation Study Group 24 (edit. by De Reuck, A. V. S., and Knight, J.), 81 (J. and A. Churchill, London, 1966).
Wissler, R. W., Ann. Rev. Microbiol., 16, 265 (1962).
Benaceraff, B., and McCluskey, R. T., Ann. Rev. Microbiol., 17, 263 (1963).
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SHERBET, G., LAKSHMI, M. Morphogenetic Properties of Follicle-stimulating Hormone: Evidence from Effects of Anti-gonadotropin Sera on Developing Chick Embryos. Nature 217, 1257–1258 (1968). https://doi.org/10.1038/2171257a0
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DOI: https://doi.org/10.1038/2171257a0
