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Growth-promoting Effect of Lysolecithin on Chinese Hamster Cells in vitro

Abstract

WHILE the importance of amino-acids1,2, salts3 and vitamins4 for growth of mammalian cells in culture is well established, the role of lipids remains uncertain. With the exception of free fatty acids5, no naturally occurring lipids such as glycerides, phospholipids or cholesterol have been shown to promote growth of mammalian cells in vitro.

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References

  1. Eagle, H., J. Biol. Chem., 214, 839 (1955).

    CAS  PubMed  Google Scholar 

  2. Levintow, L., Eagle, H., and Piez, K. A., J. Biol. Chem., 227, 929 (1957).

    CAS  PubMed  Google Scholar 

  3. Eagle, H., Arch. Biochem. Biophys., 61, 356 (1956).

    Article  CAS  Google Scholar 

  4. Eagle, H., J. Exp. Med., 102, 595 (1955).

    Article  CAS  Google Scholar 

  5. Ham, R. G., Science, 140, 802 (1963).

    Article  ADS  CAS  Google Scholar 

  6. Lands, W. E. M., J. Biol. Chem., 235, 2233 (1960).

    CAS  PubMed  Google Scholar 

  7. Newman, H. A. I., Lin, C. T., and Zilversmit, D. B., J. Lipid Res., 2, 403 (1961).

    CAS  Google Scholar 

  8. Phillips, G. B., Proc. US Nat. Acad. Sci., 43, 566 (1957).

    Article  ADS  CAS  Google Scholar 

  9. Switzer, S., and Eder, H. A., J. Lipid Res., 6, 506 (1965).

    CAS  PubMed  Google Scholar 

  10. Stein, Y., and Stein, O., Biochim. Biophys. Acta, 116, 95 (1966).

    Article  CAS  Google Scholar 

  11. Stein, O., and Stein, Y., Biochim. Biophys. Acta, 137, 232 (1967).

    Article  CAS  Google Scholar 

  12. Goodman, D. S., Science, 125, 1296 (1957).

    Article  ADS  CAS  Google Scholar 

  13. Stein, Y., and Stein, O., Biochim. Biophys. Acta, 106, 527 (1965).

    Article  CAS  Google Scholar 

  14. Parker, F., and Peterson, N. F., J. Lipid Res., 6, 455 (1965).

    CAS  Google Scholar 

  15. Eagle, H., Oyama, V. I., Levy, M., and Freeman, A. E., J. Biol. Chem., 227, 929 (1957).

    PubMed  Google Scholar 

  16. Munder, P. G., Ferber, E., and Fischer, H., Z. Naturforsch., 20 b, 1048 (1965).

    Article  CAS  Google Scholar 

  17. Dole, V. P., and Meinertz, H., J. Biol. Chem., 235, 2595 (1960).

    CAS  Google Scholar 

  18. Dole, V. P., James, A. T., Webb, J. P. W., Rizack, M. A., and Sturman, M. F., J. Clin. Invest., 38, 1544 (1959).

    Article  CAS  Google Scholar 

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NILAUSEN, K. Growth-promoting Effect of Lysolecithin on Chinese Hamster Cells in vitro. Nature 217, 268–269 (1968). https://doi.org/10.1038/217268a0

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