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Fine Structure of Nerve Fibres in Smooth Muscle of the Vas Deferens in Normal and Reserpinized Rats

Nature volume 217, pages 279–281 (1968)Cite this article

Abstract

IT is evident from Thaemert's1 review that the intra-axonal granular vesicles are generally considered to be the site of storage of catecholamines in autonomic nerves. It has also been shown2–7 that reserpine has a depleting effect on these amine stores in both peripheral and central nervous systems. No quantitative data on the effect of reserpine on various types of granular vesicles have been published, so a study of the effect of this drug on the nerve fibres of the vas deferens of the rat was undertaken.

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References

  1. Thaemert, J. C., J. Cell. Biol., 28, 37 (1966).

    Article  CAS  Google Scholar 

  2. Richardson, K. C., Biochem. Pharmacol., 12 (Suppl.), 10 (1963).

    Google Scholar 

  3. Burnstock, G., and Merrillees, N. C. R., Proc. Second Intern. Pharmacol. Meeting, Prague (edit. by Bulbring, D.), 1 (1964).

    Google Scholar 

  4. Devine, C. E., and Laverty, R., Proc. Univ. Otago Med. Sch., 43, 17 (1965).

    Google Scholar 

  5. Hokfelt, T., Experientia, 22, 56 (1966).

    Article  CAS  Google Scholar 

  6. Bloom, F. E., and Barnett, R. J., Nature, 210, 599 (1966).

    Article  ADS  CAS  Google Scholar 

  7. Van Ordern, L. C., Bloom, F. E., Barnett, R. J., and Giarman, N. J., J. Pharmacol. Exp. Therap., 154, 185 (1966).

    Google Scholar 

  8. Richardson, K. C., J. Anat., 96, 427 (1962).

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Richardson, K. C., Amer. J. Anat., 114, 173 (1964).

    Article  CAS  Google Scholar 

  10. Grillo, M. A., J. Cell. Biol., 27, 136a (1965).

    Google Scholar 

  11. Burn, J. H., and Rand, M. J., Nature, 184, 163 (1959).

    Article  ADS  Google Scholar 

  12. Silva, D. G., Anat. Rec., 158, 21 (1967).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Anatomy, Monash University, Melbourne, Australia

    KENNETH E. FARRELL

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  1. KENNETH E. FARRELL
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FARRELL, K. Fine Structure of Nerve Fibres in Smooth Muscle of the Vas Deferens in Normal and Reserpinized Rats. Nature 217, 279–281 (1968). https://doi.org/10.1038/217279a0

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