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Failure to detect Interferon in the Urine of Persons with Virus Infections

Abstract

WHEN rabbits or mice are inoculated intravenously with interferon or with an inducer of interferon formation, interferon appears in their urine1–6. Indeed, with rabbits, appreciably higher concentrations can be found at the same time in the urine than in the serum2–4. In contrast, we report here two studies in which interferon was not detected in urine from humans with viral infections.

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BUCKNALL, R., FINTER, N. & DRAPER, C. Failure to detect Interferon in the Urine of Persons with Virus Infections. Nature 217, 462–463 (1968). https://doi.org/10.1038/217462a0

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