Abstract
A NUMBER of observations suggest that human breast cancer develops under hormonal influence. Several such observations include: (a) breast cancer is predominantly a disease of women; (b) the administration of oestrogenic materials produces breast tumours in experimental animals1; (c) the course of breast cancer is influenced by ablative endocrine procedures or by the administration of exogenous hormones in both humans and experimental animals2–4; and (d) the length of the menstruating years and the number of pregnancies affect the frequency of the disease in any given population5,6.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lacassagne, A., CR Acad. Sci., 195, 630 (1932).
McDonald, I., Surg. Gynecol. Obstet., 115, 215 (1962).
Haddow, A., Watkinson, J. M., and Paterson, E., Brit. Med. J., ii, 393 (1944).
Huggins, C., Briziarelli, G., and Sutton, jun., H., J. Exp. Med., 100, 25 (1959).
Logan, W. P. D., Lancet, ii, 1199 (1953).
Lilienfeld, A. M., Cancer Res., 23, 1503 (1963).
Crowley, L. G., Demetriou, J. A., Kotin, P., Donovan, A. J., and Kushinsky, S., Cancer Res., 25, 371 (1965).
Brown, J. B., in Endocrine Aspects of Breast Cancer, 197 (E. and S. Livingstone, Ltd., Edinburgh, 1958).
Marmorston, J., Crowley, L. G., Myers, S. M., Stern, E., and Hopkins, C. E., Amer. J. Obstet. Gynecol., 92, 447 (1965).
Schweppe, J. S., Jungman, R. A., and Lewin, I., Cancer, 20, 155 (1967).
Bulbrook, R. D., Hayward, J. L., Spicer, C. C., and Thomas, B. S., Lancet, ii, 1235 (1962).
Strauss, J. S., and Pochi, P. E., Rec. Prog. Hormone Res., 19, 385 (1963).
Pochi, P. E., and Strauss, J. S., in Advances in Biology of Skin (edit. by Montagna, W.), 6, 121 (Pergamon Press, NY, 1965).
Pochi, P. E., and Strauss, J. S., Amer. Med. Assoc. Arch. Derm., 88, 729 (1963).
Strauss, J. S., and Kligman, A. M., J. Invest. Derm., 36, 309 (1961).
Pochi, P. E., Strauss, J. S., and Mescon, H., J. Invest. Derm., 41, 391 (1963).
Pochi, P. E., and Strauss, J. S., J. Invest. Derm. (in the press).
Strauss, J. S., and Pochi, P. E., J. Invest. Derm., 36, 293 (1961).
Lipsett, M. B., and Korenman, S. G., J. Amer. Med. Assoc., 190, 147 (1964).
Segre, E. J., Klaiber, E. L., Lobotsky, J., and Lloyd, C. W., Ann. Rev. Med., 15, 315 (1964).
Grattarola, R., J. Endocrinol., 38, 77 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KRANT, M., BRANDRUP, C., GREENE, R. et al. Sebaceous Gland Activity in Breast Cancer. Nature 217, 463–465 (1968). https://doi.org/10.1038/217463b0
Received:
Revised:
Published:
Issue date:
DOI: https://doi.org/10.1038/217463b0
This article is cited by
-
Lactation, Sebum Excretion and Melanocyte-stimulating Hormone
Nature (1973)
-
Control of Sebum Secretion by the Posterior Pituitary
Nature (1972)
