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Oncogenicity of Mixtures of Adeno-associated Virus and Adenovirus Type 12

Abstract

THE presence of adeno-associated virus (AAV) in certain stocks of various adenovirus types is well documented1–4. These viruses (four known serotypes) depend on adenovirus for replication, but at the same time depress the production of infectious adenovirus and virion antigens2.

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References

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GILDEN, R., KERN, J., BEDDOW, T. et al. Oncogenicity of Mixtures of Adeno-associated Virus and Adenovirus Type 12. Nature 219, 80–81 (1968). https://doi.org/10.1038/219080a0

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