Abstract
ONE of the most striking and significant developments in synthetic chemistry has been the use of biological systems to achieve chemical transformations, especially the oxidation-reduction of steroids and alkaloids. Based on an analogous biological system, we have attempted to transform aflatoxin B1, a toxic secondary metabolite of Aspergillus flavus, by employing a known steroid-hydroxylating micro-organism.
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DETROY, R., HESSELTINE, C. Isolation and Biological Activity of a Microbial Conversion Product of Aflatoxin B1. Nature 219, 967 (1968). https://doi.org/10.1038/219967a0
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DOI: https://doi.org/10.1038/219967a0
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