Abstract
PREVIOUS studies have identified the 5′ terminus of several bacteriophage RNAs, including f2, as pppGp1–3. A number of other experiments using phage RNA and fragments derived therefrom as messenger in an in vitro amino-acid incorporating system have led to the suggestion that the viral coat protein is encoded near this 5′ end3–6. This interpretation depends on assumptions made about the translation of fragmented RNA or the causes of differential rates of protein synthesis from different cistrons in vitro.
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References
Roblin, R., J. Mol. Biol., 31, 51 (1968).
Watanabe, M., and August, J. T., Proc. US Nat. Acad. Sci., 59, 513 (1968).
Lodish, H. F., Nature (in the press).
Engelhardt, D. L., Webster, R. E., and Zinder, N. D., J. Mol. Biol., 29, 45 (1967).
Engelhardt, D. L., Robertson, H. D., and Zinder, N. D., Proc. US Nat. Acad. Sci., 59, 972 (1968).
Spahr, P. F., and Gesteland, R. F., Proc. US Nat. Acad. Sci., 59, 876 (1968).
Erikson, R. L., and Franklin, R. M., Bact. Rev., 30, 267 (1966).
Webster, R. E., Engelhardt, D. L., Zinder, N. D., and Konigsberg, W., J. Mol. Biol., 29, 27 (1967).
Robertson, H. D., Webster, R. E., and Zinder, N. D., J. Biol. Chem., 243, 82 (1968).
Franklin, R. M., Proc. US Nat. Acad. Sci., 55, 1504 (1966).
Singh, H., and Lane, B., Canad. J. Biochem., 42, 87 (1964).
McLennan, B. D., and Lane, B. G., Canad. J. Biochem., 46, 81 (1968).
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ROBERTSON, H., ZINDER, N. Identification of the Terminus of Nascent f2 Bacteriophage RNA. Nature 220, 69 (1968). https://doi.org/10.1038/220069a0
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DOI: https://doi.org/10.1038/220069a0