Abstract
Nuclei isolated from human peripheral blood lymphocytes stimulated by phytohaemagglutinin have a greater capacity to prime for nucleotide incorporation into RNA in the presence of exogenous bacterial RNA polymerase than nuclei from unstimulated lymphocytes.
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Bond, V. P., Fliedner, T. M., Cronkite, E. P., Rubini, J. R., Brecher, G., and Schork, P. K., Acta Haematol., 21, 1 (1959).
Cooper, E. H., Biochem. J., 78, 21 (1961).
Torelli, U., Grossi, G., Artusi, T., and Emilia, G., Acta Haematol., 30, 129 (1963).
Buckton, K. E., and Pike, M. C., Nature, 202, 714 (1964).
Nowell, P. C., Cancer Research, 20, 462 (1960).
Hastings, J., Freedman, S., Rendon, O., Cooper, H. L., and Hirschhorn, K., Nature, 192, 1214 (1961).
McIntyre, O. R., and Ebaugh, jun., F. G., Blood, 19, 443 (1962).
Bach, F., and Hirschhorn, K., Exp. Cell Res., 32, 592 (1963).
Bender, M. A., and Prescott, D. M., Exp. Cell Res., 27, 221 (1962).
Frenster, J. H., Allfrey, V. G., and Mirsky, A. E., Proc. US Nat. Acad. Sci., 50, 1026 (1963).
Marshall, W. H., and Roberts, K. B., Quart. J. Exp. Physiol., 48, 146 (1963).
Quaglino, D., Hayhoe, F. G. J., and Flemans, R. J., Nature, 196, 338 (1962).
Gropp, A., and Fischer, R., Virchows Arch. Path. Anat., 338, 64 (1964).
Hirschhorn, R., Kaplan, J. M., Goldberg, A. F., Hirschhorn, K., and Weissmann, G., Science, 147, 55 (1965).
Wheelock, E. F., Science, 149, 310 (1965).
Coulson, A. S., Quart. J. Exp. Physiol., 50, 271 (1965).
Hirschhorn, R., Hirschhorn, K., and Weissmann, G., Blood, 30, 84 (1967).
Lukas, Z. J., Science, 156, 1237 (1967).
Loeb, L. A., Agarwal, S. S., and Woodside, A. M., Proc. US Nat. Acad. Sci., 61, 827 (1968).
Ripps, C., and Hirschhorn, K., Clin. and Exptl. Immunology, 2, 377 (1967).
Torelli, U. L., Henry, P. H., and Weissman, S. M., J. Clin. Invest., 47, 1083 (1968).
Cooper, H. L., J. Biol. Chem., 243, 34 (1968).
Pogo, B. G. T., Allfrey, V. G., and Mirsky, A. E., Proc. US Nat. Acad. Sci., 55, 805 (1966).
Kleinsmith, L. J., Allfrey, V. G., and Mirsky, A. E., Proc. US Nat. Acad. Sci., 55, 1182 (1966).
Bonner, J., Dahmus, M. E., Fambrough, D., Wang, R. C., Marushige, K., and Tuan, D. Y. H., Science, 159, 47 (1968).
Allfrey, V. G., Littau, V. C., and Mirsky, A. E., Proc. US Nat. Acad. Sci., 49, 414 (1963).
Frenster, J. H., Nature, 206, 680 (1965).
Hirschhorn, R., Brittinger, G., Weissmann, G., and Hirschhorn, K., J. Cell Biol., 37, 412 (1968).
Brittinger, G., Hirschhorn, R., Hirschhorn, K., and Weissmann, G., J. Cell Biol., 40, 843 (1969).
Brittinger, G., Hirschhorn, R., Douglas, S. D., and Weissmann, G., J. Cell Biol., 37, 394 (1968).
Weiss, S. B., Proc. US Nat. Acad. Sci., 46, 1020 (1960).
Sadowski, P. D., and Steiner, J. W., J. Cell Biol., 32, 147 (1967).
Pogo, A. O., Allfrey, V. G., and Mirsky, A. E., Proc. US Nat. Acad Sci., 56, 550 (1966).
Church, R. B., and McCarthy, B. J., J. Mol. Biol., 23, 459 (1967).
Sullivan, D. T., Proc. US Nat. Acad. Sci., 59, 846 (1968).
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HIRSCHHORN, R., TROLL, W., BRITTINGER, G. et al. Template Activity of Nuclei from Stimulated Lymphocytes. Nature 222, 1247–1250 (1969). https://doi.org/10.1038/2221247a0
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DOI: https://doi.org/10.1038/2221247a0
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