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Action of Sparsomycin on Ribosome-catalysed Peptidyl Transfer

Abstract

Sparsomycin inhibits protein biosynthesis by inducing the formation of an inert complex between the peptidyl donor substrate and the 50S ribosomal subunit.

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MONRO, R., CELMA, M. & VAZQUEZ, D. Action of Sparsomycin on Ribosome-catalysed Peptidyl Transfer. Nature 222, 356–358 (1969). https://doi.org/10.1038/222356a0

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