Abstract
The RNA polymerase σ factor is required for the initiation of RNA synthesis. After initiation σ is released from the polymerase-factor complex and from the DNA template, and may then be re-used by another polymerase molecule to initiate a new RNA chain.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Burgess, R. R., Travers, A. A., Dunn, J. J., and Bautz, E. K. F., Nature, 221, 43 (1969).
Bremer, H., Konrad, M. W., Gaines, K., and Stent, G. S., J. Mol. Biol., 13, 540 (1965).
Maitra, U., and Hurwitz, J., Proc. US Nat. Acad. Sci., 54, 815 (1965).
Umezawa, H., Mizuno, S., Yamazaki, H., and Nitta, K., J. Antibiotics, 21, 234 (1968).
Burgess, R. R., thesis, Harvard University (1969).
de St. Groth, S. F., Webster, R. G., and Datyner, A., Biochim. Biophys. Acta, 71, 377 (1963).
Richardson, J. P., Proc. US Nat. Acad. Sci., 55, 1616 (1966).
Stevens, A., J. Biol. Chem., 244, 425 (1969).
Maitra, U., Nakata, Y., and Hurwitz, J., J. Biol. Chem., 242, 4908 (1967).
Bremer, H., and Bruner, R., Mol. Gen. Genet., 107, 6 (1968).
Bremer, H., and Konrad, M. W., Proc. US Nat. Acad. Sci., 51, 801 (1964).
Bautz, E. K. F., and Dunn, J. J., Biochem. Biophys. Res. Commun., 34, 230 (1969).
Krakow, J. S., Daley, K., and Karstadt, M., Proc. US Nat. Acad. Sci. (in the press, 1969).
Chamberlin, M. J., and Berg, P., Proc. US Nat. Acad. Sci., 48, 81 (1962).
Stevens, A., and Henry, J., J. Biol. Chem., 239, 196 (1964).
Babinet, C., Biochem. Biophys. Res. Commun., 26, 639 (1967).
Walter, G., Zillig, W., Palm, P., and Fuchs, E., Europ. J. Biochem., 3, 194 (1967).
Frederick, E. W., Maitra, U., and Hurwitz, J., J. Biol. Chem., 244, 413 (1969).
Glynn, I. M., and Chappell, J. B., Biochem. J., 90, 147 (1964).
Shapiro, A., Vinuela, E., and Maizel, J. V., Biochem. Biophys. Res. Commun., 28, 815 (1967).
Wehrli, W., Knusel, F., and Staehelin, M., Biochem. Biophys. Res. Commun., 32, 284 (1968).
Tocchini-Valentini, G. P., Marino, P., and Colvill, A. J., Nature, 220, 275 (1968).
Ezekiel, D. H., and Hutchins, J. E., Nature, 220, 276 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
TRAVERS, A., BURGESS, R. Cyclic Re-use of the RNA Polymerase Sigma Factor. Nature 222, 537–540 (1969). https://doi.org/10.1038/222537a0
Issue date:
DOI: https://doi.org/10.1038/222537a0
This article is cited by
-
Analysis of miRNA-seq combined with gene expression profile reveals the complexity of salinity stress response in Oryza sativa
Acta Physiologiae Plantarum (2017)
-
Cloning, High Expression and Purification of Recombinant Human Intereferon-β-1b in Escherichia coli
Applied Biochemistry and Biotechnology (2009)
-
Advances in bacterial promoter recognition and its control by factors that do not bind DNA
Nature Reviews Microbiology (2008)
-
Optimization of the AT-content of Codons Immediately Downstream of the Initiation Codon and Evaluation of Culture Conditions for High-level Expression of Recombinant Human G-CSF in Escherichia coli
Molecular Biotechnology (2008)
-
Sigma, from the start
Nature Reviews Molecular Cell Biology (2005)
