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X-ray Diffraction Study of the Interaction of Phospholipids with Cytochrome c in the Aqueous Phase

Abstract

STRUCTURAL features of model complexes formed between phospholipids and proteins throw light on the molecular architecture of both biological membranes and serum lipoproteins. The polymorphic phases of both synthetic and natural phospholipid–water systems have been extensively studied1–6, but little work has been reported on phospholipid–protein–water systems7–10.

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References

  1. Luzzati, V., and Husson, F., J. Cell Biol., 12, 207 (1962).

    Article  CAS  Google Scholar 

  2. Reiss-Husson, F., J. Mol. Biol., 25, 363 (1967).

    Article  CAS  Google Scholar 

  3. Chapman, D., Williams, R. M., and Ladbrooke, B. D., Chem. Phys. Lipids, 1, 445 (1967).

    Article  CAS  Google Scholar 

  4. Small, D., J. Lipid Res., 8, 551 (1967).

    PubMed  CAS  Google Scholar 

  5. Gulik-Krzywicki, T., Rivas, E., and Luzzati, V., J. Mol. Biol., 27, 303 (1967).

    Article  CAS  Google Scholar 

  6. Levine, Y. K., Bailey, A. I., and Wilkins, M. H. F., Nature, 220, 577 (1968).

    Article  ADS  CAS  Google Scholar 

  7. Palmer, K. J., Schmitt, F. O., and Chargaff, E., J. Cell Comp. Physiol., 18, 43 (1941).

    Article  CAS  Google Scholar 

  8. Stoeckenius, W., in CIBA Foundation Symposium on Principles of Biomolecular Organisation, 430–432 (Churchill, London, 1966).

    Google Scholar 

  9. Stoeckenius, W., in Protides of the Biological Fluids (edit. Peeters, H.), 378–380 (Elsevier, Amsterdam, 1966).

    Google Scholar 

  10. Papahadjopoulos, D., and Miller, N., Biochim. Biophys. Acta, 135, 624 (1967).

    Article  CAS  Google Scholar 

  11. Das, M. L., and Crane, F. L., Biochemistry, 3, 696 (1964).

    Article  CAS  Google Scholar 

  12. Das, M. L., Haak, E. D., and Crane, F. L., Biochemistry, 4, 859 (1965).

    Article  CAS  Google Scholar 

  13. Shipley, G. G., Leslie, R. B., and Chapman, D., Biochim. Biophys. Acta 173, 1 (1969).

    Article  CAS  Google Scholar 

  14. Singleton, W. S., Gray, M. S., Brown, M. L., and White, J., J. Amer. Oil Chem. Soc., 42, 53 (1965).

    Article  CAS  Google Scholar 

  15. Elkes, J., and Finean, J. B., Disc. Farad. Soc., 6, 134 (1949).

    Article  Google Scholar 

  16. Ladbrooke, B. D., Jenkinson, T. J., Kamat, V. B., and Chapman, D., Biochim. Biophys. Acta, 164, 101 (1968).

    Article  CAS  Google Scholar 

  17. Palmer, K. J., and Schmitt, F. O., J. Cell Comp. Physiol., 17, 355 (1941).

    Article  Google Scholar 

  18. Korn, E. D., Science, 153, 1491 (1966).

    Article  ADS  CAS  Google Scholar 

  19. Fontell, K., Mandell, L., Lehtinen, H., and Ekwall, P., Acta Polytechnica Scand., Chem. and Metallurgy Ser. No. 74 (1968).

  20. Dickerson, R. E., Kopka, M. L., Borders, C. L., Varnum, J., and Weinzierl, J. E., J. Mol. Biol., 29, 77 (1967).

    Article  CAS  Google Scholar 

  21. Finean, J. B., Coleman, R., Green, W. G., and Limbrick, A. R., J. Cell Sci., 1, 287 (1966).

    PubMed  CAS  Google Scholar 

  22. Thompson, J. E., Coleman, R., and Finean, J. B., Biochim. Biophys. Acta, 150, 405 (1968).

    Article  CAS  Google Scholar 

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SHIPLEY, G., LESLIE, R. & CHAPMAN, D. X-ray Diffraction Study of the Interaction of Phospholipids with Cytochrome c in the Aqueous Phase. Nature 222, 561–562 (1969). https://doi.org/10.1038/222561a0

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