Influence of Dietary Liquid Glucose, Sucrose and Fructose on Body Fat Formation

Abstract

ADULT male rats fed for 6 months on diets containing sucrose BP, or more especially fructose, had more carcass fat than rats fed diets containing liquid glucose BPC (a partial hydrolysato of starch), anhydrous dextrose BP (d-glucose) or a standard laboratory diet¹. In a preliminary experiment with mature male baboons, even though similar calorie intakes were achieved, significantly more abdominal fat was deposited on a high sucrose diet than on a high liquid glucose diet². Liquid glucose is Diet fed used as a source of dietary carbohydrate, especially during convalescence^3,4 and in the dietary management of renal failure^5,6 when it may provide a large proportion of the daily calorie intake. The finding that a liquid glucose diet may lead to less deposition of body fat than a sucrose diet is an unexpected observation important to food manufacturers. We have investigated it further.