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Development of Transplanted Imaginal Disks in X-irradiated Housefly Pupae

Abstract

TRANSPLANTATION and parabiotic experiments have shown that, in irradiated embryos of vertebrates, direct damage to organ rudiments is primarily responsible for developmental abnormalities1–4. Although the irradiated environment per se does not adversely influence the development of normal organ transplants, it does seem to enhance the damage in irradiated organ primordia5,6. We have carried out similar experiments in housefly pupae and observed that normal imaginal disks transplanted in irradiated pupae developed poorly. Besides, the epidermis of the irradiated host inhibited the development of transplants when they were in contact with each other.

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BHASKARAN, G., SIVASUBRAMANIAN, P. Development of Transplanted Imaginal Disks in X-irradiated Housefly Pupae. Nature 222, 786–787 (1969). https://doi.org/10.1038/222786a0

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