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New Light on How Aspirin Works

Nature volume 223, pages 35–37 (1969)Cite this article

Abstract

Aspirin and similar drugs may act by blocking the release of rabbit aorta contracting substance described in the preceding article.

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References

  1. Collier, H. O. J., Sci. Amer., 209, 96 (1963).

    Article  ADS  Google Scholar 

  2. Collier, H. O. J., Advances in Pharmacology and Chemotherapy, 7 (in the press, 1969).

  3. Adams, S. S., and Cobb, R., Nature, 181, 773 (1958).

  4. Whitehouse, M. W., Prog. Drug. Res., 8, 321 (1965).

    CAS  Google Scholar 

  5. Smith, M. J. H., in The Salicylates: a Critical Bibliographic Review (edit. by Smith, M. J. H., and Smith, P. K.), 203 (Wiley, New York, 1966).

    Google Scholar 

  6. Collier, H. O. J., and Shorley, P. G., Brit. J. Pharmacol. Chemother., 15, 601 (1960).

    Article  CAS  Google Scholar 

  7. Collier, H. O. J., and Shorley, P. G., Brit. J. Pharmacol. Chemother., 20, 345 (1963).

    Article  CAS  Google Scholar 

  8. Berry, P. A., and Collier, H. O. J., Brit. J. Pharmacol. Chemother., 23, 201 (1964).

    Article  CAS  Google Scholar 

  9. Vargaftig, B. B., de Miranda, E. P., and Lacoume, B., Nature, 222, 883 (1969).

    Article  ADS  CAS  Google Scholar 

  10. Collier, H. O. J., and Sweatman, W. J. F., Nature, 219, 864 (1968).

    Article  ADS  CAS  Google Scholar 

  11. Jaques, R., Helv. Physiol. Acta, l7, 255 (1959).

    Google Scholar 

  12. Berry, P. A., thesis, Council for National Academic Awards, London, 91 (1966).

  13. Collier, H. O. J., James, G. W. L., and Schneider, C., Nature, 212, 411 (1966).

    Article  ADS  CAS  Google Scholar 

  14. Collier, H. O. J., Dinneen, L. C., Johnson, C. A., and Schneider, C., Brit. J. Pharmacol. Chemother., 32, 295 (1968).

    Article  CAS  Google Scholar 

  15. Bhoola, K. D., Collier, H. O. J., Schachter, M., and Shorley, P. G., Brit. J. Pharmacol. Chemother., 19, 190 (1962).

    Article  CAS  Google Scholar 

  16. Collier, H. O. J., James, G. W. L., and Piper, P. J., J. Physiol., 180, 13P (1965).

    CAS  Google Scholar 

  17. Collier, H. O. J., James, G. W. L., and Piper, P. J., Brit. J. Pharmacol Chemother., 34, 76 (1968).

    Article  CAS  Google Scholar 

  18. Collier, H. O. J., Biochem. Pharmac., 10, 47 (1962).

    Article  Google Scholar 

  19. Aarsen, P. N., Brit. J. Pharmacol. Chemother., 27, 196 (1966).

    CAS  Google Scholar 

  20. Greeff, K., and Moog, E., Arch. Exp. Path. Pharmak., 248, 204 (1964).

    CAS  Google Scholar 

  21. Piper, P. J., and Vane, J. R., Nature, this issue (223, 29) (1969).

    Article  ADS  CAS  Google Scholar 

  22. Brocklehurst, W. E., and Lahiri, S. C., J. Physiol., 160, 15P (1962).

  23. Brocklehurst, W. E., J. Physiol., 151, 416 (1960).

    Article  CAS  Google Scholar 

  24. Seed, J. C., Clin. Pharmac. Ther., 6, 354 (1965).

    Article  CAS  Google Scholar 

  25. Niemegeers, C. J. E., Verbruggen, F. J., and Janssen, P. A. J., J. Pharm. Pharmacol., 16, 810 (1964).

    Article  CAS  Google Scholar 

  26. Hendershot, L. C., and Forsaith, J. L., J. Pharmacol. Exp. Ther., 125, 237 (1959).

    CAS  PubMed  Google Scholar 

  27. Whittle, B. A., Brit. J. Pharmacol. Chemother., 22, 246 (1964).

    Article  CAS  Google Scholar 

  28. Collier, H. O. J., Hammond, A. R., Horwood-Barrett, S., and Schneider, C., Nature, 204, 1316 (1964).

    Article  ADS  CAS  Google Scholar 

  29. Guzman, F., Braun, C., Lim, R. K. S., Potter, G. D., and Rodgers, D. W., Arch. Intern. Pharmacodyn. Ther., 149, 571 (1964).

    CAS  Google Scholar 

  30. Adams, S. S., and Cobb, R., in Salicylates: an International Symposium (edit. by Dixon, A. St J., Martin, B. K., Smith, M. J. H., and Wood, P. H. N.), 127 (Churchill, London, 1963).

    Google Scholar 

  31. O'Brien, J. R., Lancet, 1, 779 (1968).

    Article  CAS  Google Scholar 

  32. Vargaftig, B. B., Extperientia, 22, 182 (1966).

    Article  CAS  Google Scholar 

  33. Collier, H. O. J., Dinneen, L. C., Perkins, A. C., and Piper, P. J., Arch. Exp. Path. Pharmak., 259, 159 (1968).

    Article  CAS  Google Scholar 

  34. Truelove, L. H., and Duthie, J. J. R., Ann. Rheum. Dis., 18, 137 (1959).

    Article  CAS  Google Scholar 

  35. Haining, C. G., Brit. J. Pharmacol. Chemother., 21, 104 (1963).

    Article  CAS  Google Scholar 

  36. Hinshaw, L. B., Solomon, L. A., Erdös, E. G., Reins, D. A., and Gunter, B. J., J. Pharmacol. Exp. Ther., 157, 665 (1957).

    Google Scholar 

  37. Northover, B. J., and Subramanian, G., Brit. J. Pharmacol. Chemother., 17, 107 (1961).

    Article  CAS  Google Scholar 

  38. Lim, R. K. S., Guzman, F., Rodgers, D. W., Goto, K., Braun, C., Dickerson, C. D., and Engle, R. J., Arch. Intern. Pharmacodyn. Therap., 152, 25 (1964).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pharmacological Research, Division of Medical and Scientific Affairs, Parke-Davis and Company, Hounslow, Middlesex

    H. O. J. COLLIER

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  1. H. O. J. COLLIER
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COLLIER, H. New Light on How Aspirin Works. Nature 223, 35–37 (1969). https://doi.org/10.1038/223035a0

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