Abstract
The σ factor of E. coli RNA polymerase selectively promotes transcription of T4 phage pre-early genes. The residual activity of the minimal enzyme on T4 DNA is caused by random initiation on both strands of the entire T4 DNA molecule.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Burgess, R. R., Travers, A. A., Dunn, J. J., and Bautz, E. K. F., Nature, 221, 43 (1969).
Travers, A. A., and Burgess, R. R., Nature, 222, 537 (1969).
Milanesi, G., Brody, E. N., and Geiduschek, E. P., Nature, 22l, 1014 (1969).
Walter, G., Seifert, W., and Zillig, W., Biochem. Biophys. Res. Commun., 30, 240 (1968).
Bautz, E. K. F., and Dunn, J. J., Biochem. Biophys. Res. Commun., 34, 230 (1969).
Kasai, T., and Bautz, E. K. F., J. Mol. Biol., 41, 401 (1969).
Colvill, A. J. E., Kanner, L. C., Tocchini-Valentini, G. P., Sarnat, M., and Geiduschek, E. P., Proc. US Nat. Acad. Sci., 53, 1140 (1965).
Bolle, A., Epstein, R. H., Salser, W., and Geiduschek, E. P., J. Mol. Biol., 33, 339 (1968).
Chamberlin, M., and Berg, P., Proc. US Nat. Acad. Sci., 48, 81 (1962).
Bautz, E. K. F., and Hall, B. D., Proc. US Nat. Acad. Sci., 48, 400 (1962).
Bautz, E. K. F., and Reilly, E. E., Science, 151, 328 (1966).
Bolle, A., Epstein, R. H., Salser, W., and Geiduschek, E. P., J. Mol. Biol., 31, 325 (1969).
Hosoda, J., and Levinthal, C., Virology, 34, 709 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BAUTZ, E., BAUTZ, F. & DUNN, J. E. coli σ Factor: A Positive Control Element in Phage T4 Development. Nature 223, 1022–1024 (1969). https://doi.org/10.1038/2231022a0
Received:
Issue date:
DOI: https://doi.org/10.1038/2231022a0
This article is cited by
-
A physical map of bacteriophage T4 including the positions of strong promoters and terminators recognized in vitro
Molecular and General Genetics MGG (1984)
-
Mechanistic aspects of promoter binding and chain initiation by RNA polymerase
Molecular and Cellular Biochemistry (1982)
-
Physical mapping of bacteriophage T4
Molecular and General Genetics MGG (1981)
-
A mutation affecting the σ subunit of RNA polymerase changes transcriptional specificity
Nature (1978)
-
Multiple effects of an RNA polymerase β' mutation on in vitro transcription
Molecular and General Genetics MGG (1977)
