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Renin-like Activity in the Plasma of Anephric Men

Nature volume 223, page 1156 (1969)Cite this article

Abstract

RENIN-LIKE activity has been found in several extra renal tissues1–3, and the isolated perfused rabbit uterus releases renin-like material in response to pharmacological stimulants4. Capelli et al.5 found plasma renin-like activity in anephric women but not in two anephric men. Finding detectable renin-like activity only in the uterus at post-mortem in one female, they postulated uterus as the likely source of the plasma renin-like material. The present study provides evidence of renin-like material in male as well as female anephric patients, thus implicating a source other than uterus for some of this material.

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Author notes

  1. J. K. MCKENZIE

    Present address: Department of Medicine, University of Manitoba, 100 Medical College, Winnipeg, 3, Manitoba, Canada

Authors and Affiliations

  1. Wellcome Medical Research Institute, Department of Medicine, University of Otago, and Medical Unit, Department of Medicine, Auckland University Medical School, New Zealand

    J. K. MCKENZIE & J. Z. MONTGOMERIE

Authors
  1. J. K. MCKENZIE
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  2. J. Z. MONTGOMERIE
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MCKENZIE, J., MONTGOMERIE, J. Renin-like Activity in the Plasma of Anephric Men. Nature 223, 1156 (1969). https://doi.org/10.1038/2231156a0

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