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Induction of Alcohol Dehydrogenase in the Rat

Nature volume 223, pages 199–200 (1969)Cite this article

Abstract

ETHANOL is metabolized to acetaldehyde by a zinc containing enzyme, alcohol dehydrogenase (ADH)1–4. This is a rate limiting step and is dependent on the presence of nicotine adenine dinucleotide (NAD) which acts as a hydrogen acceptor5,6. Over 90 per cent of the alcohol ingested is oxidized and it is currently assumed that this occurs entirely in the liver7,8.

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Authors and Affiliations

  1. Department of Gastroenterology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, 2050, Australia

    STEVEN P. MISTILIS & ANGELA BIRCHALL

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  1. STEVEN P. MISTILIS
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  2. ANGELA BIRCHALL
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MISTILIS, S., BIRCHALL, A. Induction of Alcohol Dehydrogenase in the Rat. Nature 223, 199–200 (1969). https://doi.org/10.1038/223199a0

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