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Attenuation of Rhinovirus Type 15 for Humans

Nature volume 223, pages 213–214 (1969)Cite this article

Abstract

HERE we describe results which indicate that third passage in human embryonic lung fibroblasts (WI-26) resulted in attenuation of rhinovirus type 15, and suggest that such attenuated strains might offer an approach to control of rhinovirus common colds.

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References

  1. Knight, V., in Progress in Medical Virology (edit. by Barger, E., and Melnick, J. L.), 6, 1 (S. Karger, Basel and New York, 1964).

    Google Scholar 

  2. Cate, T. R., Couch, R. B., and Johnson, K. M., J. Clin. Invest., 43, 56 (1964).

    Article  CAS  Google Scholar 

  3. Couch, R. B., Cate, T. R., Douglas, jun., R. G., Gerone, P. J., and Knight, V., Bact. Rev., 30, 517 (1966).

    PubMed  CAS  Google Scholar 

  4. Douglas, jun., R. G., Lindgren, K. M., and Couch, R. B., New Engl. J. Med., 279, 776 (1968).

    Article  Google Scholar 

  5. Douglas, jun., R. G., Couch, R. B., Cate, T. R., Gerone, P. J., and Knight, V., Amer. Rev. Resp. Dis., 94, 159 (1966).

    PubMed  Google Scholar 

  6. Fleet, W. F., Couch, R. B., Cate, T. R., and Knight, V., Amer. J. Epidemiol., 82, 185 (1965).

    Article  CAS  Google Scholar 

  7. Gwaltney, J. M., and Jordan, jun., W. S., Bact. Rev., 28, 409 (1964).

    PubMed  Google Scholar 

  8. Mufson, M. A., Ludwig, W. M., James, H. D. T., Gould, L. W., Rourke, J. A., Holper, J. C., and Chanock, R. M., J. Amer. Med. Assoc., 186, 578 (1963).

    Article  CAS  Google Scholar 

  9. Doggett, J. E., Bynoe, M. L., and Tyrrell, D. A. J., Brit . Med. J., 1, 34 (1963).

    Article  CAS  Google Scholar 

  10. Cate, T. R., Rossen, R. D., Douglas, jun., R. G., Butler, W. T., and Couch, R. B., Amer. J. Epidemiol., 84, 352 (1966).

    Article  CAS  Google Scholar 

  11. Smith, C. B., Purcell, R. H., Bellanti, J. A. and Chanock, R. M., New Engl. J. Med., 275, 1145 (1966).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Baylor College of Medicine, Departments of Microbiology and Medicine, Houston, Texas

    R. GORDON DOUGLAS JUN. & R. B. COUCH

Authors
  1. R. GORDON DOUGLAS JUN.
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  2. R. B. COUCH
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DOUGLAS, R., COUCH, R. Attenuation of Rhinovirus Type 15 for Humans. Nature 223, 213–214 (1969). https://doi.org/10.1038/223213b0

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