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Structural Difference in Sites on the Surface Membrane of Normal and Transformed Cells

Abstract

About 85 per cent of binding sites for the protein concanavalin A that are exposed on the surface membrane of transformed cells, are in a cryptic form on normal cells. The change in structure of the surface membrane resulting in the exposure of surface sites may produce the change in cellular regulatory mechanism that is associated with transformation.

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INBAR, M., SACHS, L. Structural Difference in Sites on the Surface Membrane of Normal and Transformed Cells. Nature 223, 710–712 (1969). https://doi.org/10.1038/223710a0

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