Abstract
HARRIS et al.1 have observed the suppression of the malignancy of three types of malignant cell as a result of their fusion with cells of line A9, which they considered non-malignant. Here we supplement their data with information neglected by or unavailable to them. As will be seen, this information supplies answers to at least some of the questions raised by Harris et al.1.
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References
Harris, H., Miller, O. J., Klein, G., Worst, P., and Tachibana, T., Nature, 223, 363 (1969).
Littlefield, J. W., Exp. Cell Res., 41, 190 (1966).
Barski, G., and Cornefert, F., J. Nat. Cancer Inst., 28, 801 (1962).
Scaletta, L. J., and Ephrussi, B., Nature, 205, 1169 (1965).
Defendi, V., Ephrussi, B., Koprowski, H., and Yoshida, M. C., Proc. US Nat. Acad. Sci., 57, 209 (1967).
Defendi, V., Ephrussi, B., and Koprowski, H., Nature, 203, 495 (1964).
Barski, G., Biedler, J. L., and Cornefert, F., J. Nat. Cancer Inst., 26, 865 (1961).
Silagi, S., Cancer Res., 27, 1953 (1967).
Finch, B., thesis, Western Keserve University (1968).
Nature, 223, 345 (1969).
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EPHRUSSI, B., DAVIDSON, R. & WEISS, M. Malignancy of Somatic Cell Hybrids. Nature 224, 1314–1315 (1969). https://doi.org/10.1038/2241314a0
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DOI: https://doi.org/10.1038/2241314a0
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