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Influence of Antilymphocyte Serum on DMBA Induction of Oral Carcinomas

Abstract

SURVEYING the relationships between immunity and malignant disease, Fairley1 concluded that “in man, as in animals, many tumours contain tumour-specific antigens against which the host is capable of reacting”. It is evident that an active immune system may be important in the elimination of spontaneously arising malignant cells2, but when tumour cell foci arise rapidly and in large numbers, the immune mechanism may be unable to stem the formation of an overt neoplasm.

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WOODS, D. Influence of Antilymphocyte Serum on DMBA Induction of Oral Carcinomas. Nature 224, 276–277 (1969). https://doi.org/10.1038/224276a0

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