Yttrium-90 in Gonads of Monkeys containing Strontium-90

Abstract

THE distribution of ⁹¹Y and ⁹⁰Y in tissues after intravenous injection of ⁹¹Y or of ⁹⁰Y + ⁹⁰Sr has been reviewed^1,2. This information is not very helpful in understanding the transfer of ⁹⁰Y from bone into soft tissues because of the overwhelming contribution of the directly injected Y. But if a mixture of ⁹⁰Sr and ⁹⁰Y is injected intramuscularly, ⁹⁰Sr is free to diffuse into the blood stream but the injected ⁹⁰Y is almost immobilized locally. The ⁹⁰Sr is largely taken up into the bones and in these circumstances soft tissue content of ⁹⁰Y may be an index of transport of ⁹⁰Y formed in bone out of bone and into the blood stream.